The Herbert and Florence Irving Institute for Cancer Dynamics will continue its seminar series on the topic of mathematical sciences underpinning cancer research during the 2022-2023 academic year. The monthly seminars take place on the third Wednesday of the month, 2:00-3:00 PM EST. The presentations are open to the Columbia community (in person and online) and to researchers outside Columbia (via Zoom).
On Wednesday, September 21st (2:00-3:00 PM, EST), IICD welcomes Sanja Vickovic, PhD, Assistant Professor of Biomedical Engineering (in the Herbert and Florence Irving Institute for Cancer Dynamics) and the Director of Technology Innovation and a Core Faculty at the New York Genome Center. Seminar hosted by Simon Tavaré, FRS.
The seminar will take place in person in Schermerhorn Hall 603 (Morningside Heights campus). If you wish to attend the seminar remotely, please register using the following link: https://columbiauniversity.zoom.us/meeting/register/tJwsce6rqzwvHNT0wzxrpaU9-JsYaQOftIUs
Title: Spatial Multi-Omics Technologies at Scale
Abstract: The spatial organization of cells and molecules plays a key role in tissue function in homeostasis and disease. Spatial transcriptomics has recently emerged as a key technique to capture and positionally barcode RNAs directly in tissues. Today, I will present the recent advances in the application of spatial transcriptomics at scale, by presenting Spatial Multi-Omics (SM-Omics) as a fully automated, high-throughput all-sequencing based platform for combined and spatially resolved transcriptomics and antibody-based protein measurements. SM-Omics uses DNA-barcoded antibodies, immunofluorescence or a combination thereof, to scale and combine spatial transcriptomics and spatial antibody-based multiplex protein detection.
Bio: Dr. Vickovic is currently the Director of Technology Innovation and a Core Faculty at the New York Genome Center and Assistant Professor of Biomedical Engineering (in the Herbert and Florence Irving Institute for Cancer Dynamics) at Columbia University as well as a Wallenberg Academy Fellow of the Royal Academy of Sciences and Royal Academy of Engineering at Uppsala University. Dr. Vickovic received her PhD in Genetics from the Royal Institute of Technology in Stockholm. Following her graduate work, Dr. Vickovic joined the Broad Institute of MIT and Harvard as a Wallenberg Fellow. Dr. Vickovic pioneered novel spatially resolved transcriptomics and genomics methods that enable massively parallel in situ profiling of intact tissue samples. She has vast experience in spatial and single cell genomics, data analysis and software implementations with focus on developing accessible genomic methods for use in clinics.