CINner: A New Computational Framework Sheds Light on Cancer Evolution
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Discover CINner, an innovative computational tool developed by researchers at IICD, revolutionizing how scientists study chromosomal instability in cancer. Published in PLOS Computational Biology, CINner provides deeper insights into tumor evolution and potential therapeutic interventions.
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Cancer Research Month Spotlight: Brent Stockwell's Bold Approach to Targeting Aggressive Cancers
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In honor of Cancer Research Month, we’re featuring IICD member Dr. Brent Stockwell, whose groundbreaking research explores how ferroptosis—a unique form of cell death—could be the key to eliminating aggressive, drug-resistant cancers. Learn how his work is uncovering new metabolic vulnerabilities and paving the way for future therapies.
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Cancer Research Month Spotlight: Yue Wang Uses AI to Decode Cancer’s Genetic Blueprint
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In honor of Cancer Research Month, we’re highlighting the work of IICD’s Yue Wang, whose research uses artificial intelligence and mathematical models to understand how genes regulate each other—and how those interactions go awry in cancer. Learn how his work could help uncover new targets for treatment and pave the way for more personalized therapies.
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IICD Seminar Series: May Seminar
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Tissue Stem Cells: Coping With Stress and Cancer
Hosted by: Elham Azizi, PhD
Date: May 14, 2025
Time: 2:00 PM (ET)
Location: Schermerhorn Hall 603 and via Zoom
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We’re excited to announce the promotion of Reed Black to Manager, Research Administration! In this role, Reed will continue to lead all pre- and post-award grant activities, serving as the key resource for proposals, compliance, budgeting, and sponsor communications.
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We are proud to share that Anabel Ojeda, a former participant in our Summer Research Program (SRP '23) in Elham Azizi's Lab, has been honored with the Dean Student Circle for Outstanding Academic Achievement at Adelphi University!
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We’re excited to announce that IICD is now on Bluesky! Follow us at @cancerdynamics.bsky.social to stay up to date on the latest research highlights, news, and events from across our community. Come connect with us—we’d love to see you there!
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Recent Publications from IICD Researchers
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CINner: Modeling and Simulation of Chromosomal Instability in Cancer at Single-Cell Resolution. Dinh, K. N.; Vázquez-GarcÃa, I.; Chan, A.; Malhotra, R.; Weiner, A.; McPherson, A. W.; Tavaré, S. PLOS Computational Biology 2025, 21 (4), e1012902.
Novel Devices and Biomarkers in Screening for Esophageal Squamous Cell Cancer. Januszewicz, W.; Nowicki-Osuch, K. Best Practice & Research Clinical Gastroenterology 2025, in press.
p53-Regulated Non-Apoptotic Cell Death Pathways and their Relevance in Cancer and Other Diseases. Liu, Y.; Stockwell, B. R.; Jian, X.; Gu, W. Nat Rev Mol Cell Biol 2025, in press.
ZEB2 is a Master Switch Controlling the Tumor-Associated Macrophage Program. Sheban, F.; Phan, T. S.; Xie, K.; Ingelfinger, F.; Gur, C.; Shapir Itai, Y.; Blecher-Gonen, R.; Yu, C.; Avellino, R.; Chalan, P.; Freitag, K.; Yofe, I.; Yutkin, V.; Boyeau, P.; Ergen, C.; Hong, J.; Mazuz, K.; Liu, Y.; Chen, K.; Dahan, R.; Kortylewski, M.; Yosef, N.; Weiner, A.; Amit, I. Cancer Cell 2025, in press.
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