The Gaublomme lab developed a new optical pooled screening approach called CRISPRmap, which opens new lines of inquiry in gene function. The possibility of perturbing genes and reading out the resulting phenotypes in a spatially resolved manner in tissues enables researchers to map not only cell intrinsic but also cell-extrinsic effects, which are inaccessible to in-vitro studies. The findings were recently shared in Nature Biotechnology.
 

A new paper in Genome Research introduces DIISCO, an innovative method for studying dynamic cell-cell interactions using single-cell RNA sequencing data. DIISCO represents a significant advancement in understanding how cells communicate and evolve over time, particularly in the context of cancer and immune responses. 
 

The IICD community is excited to announce the addition of the Andor Dragonfly confocal microscope to its research arsenal. This state-of-the-art tool will significantly enhance the labs' capabilities in visualizing and understanding cancer biology at the cellular level, furthering IICD's mission to pioneer advancements in cancer research.
 

IICD faculty members Genevera Allen and David Blei have been chosen to deliver an Institute of Mathematical Statistics Medallion Lecture, a high honor in the field. The Medallion Award and Lecture are prestigious recognitions, inviting just eight recipients annually to deliver a lecture based on their significant research contributions.