Faces of IICD: Beatrice Grauman,
PhD Student
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In our latest Faces of IICD video feature, we spotlight Beatrice Grauman, a PhD student in the Vicković Lab at the New York Genome Center. Her work explores how tumor-microenvironment interactions shape cancer evolution, using tools like CRISPR screening and spatial transcriptomics. Watch the video to learn what inspires Beatrice and discover her interests outside of the lab.
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GROW 2025 Returns to Columbia University
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GROW 2025 at Columbia welcomed 90 undergraduates for a weekend of inspiring talks, panels, and networking. The event empowered students envisioning a career path in the mathematical sciences and, through new connections, furthered GROW’s mission to build future generations of mathematical scientists.
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IICD Research Highlights for Breast Cancer Awareness Month
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In honor of Breast Cancer Awareness Month, we’re highlighting the groundbreaking work of IICD scientists advancing our understanding of breast cancer. Their research, along with collaborative efforts across Columbia, continues to drive progress toward more precise and effective breast cancer treatments.
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IICD Seminar Series: October Seminar
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Dissecting the Role of Aneuploidy in Cancer
Hosted by Khanh Dinh, PhD
Date: October 8, 2025
Time: 2:00 PM (ET)
Location: Schermerhorn
Hall 603 and via Zoom
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Dr. Elham Azizi will serve as a keynote speaker at the 2025 Scverse Conference, taking place Nov. 17–19 at Stanford University. Dr. Azizi will join leading researchers and innovators who advance the field of computational biology through multimodal approaches, spatial genomics and high-throughput imaging.
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Congratulations to alumna Theresa Luo (IICD SRP 22') who recently began medical school at Touro College of Osteopathic Medicine and received her white coat. As a member of our inaugural summer cohort, Theresa investigated novel fixation methods for single-cell DNA and RNA sequencing.
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Congratulations to Mathini Vaikunthan (McFaline-Figueroa's lab) on receiving an IICD Travel Award to attend the EMBO Workshop on Lineage Tracing: Dynamics, Cellular Memory, and Somatic Evolution, where she presented a poster showcasing her targeted single-cell transcriptomics method.
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IICD Welcomes New Members
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We are delighted to welcome 5 new members to the IICD and look forward to the valuable contributions they will bring to our dynamic community.
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Recent Publications from IICD Researchers
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A Graph Homomorphism Approach for Unraveling Histories of Metastatic Cancers and Viral Outbreaks under Evolutionary Constraints. Kuzmin, K.; Schmidt, H.; Kafi Kang, M.; Snir, S.; Raphael, B. J.; Skums, P. A Nature Communications 2025, 16 (1), 8027.
AMICI: Attention Mechanism Interpretation of Cell-Cell Interactions. Hong, J.; Desai, K.; Nguyen, T. D.; Nazaret, A.; Levy, N.; Ergen, C.; Plitas, G.; Azizi, E. bioRxiv 2025.
Brain-Wide Cell-Type-Specific Noradrenergic Modulation of the Transcriptome. Slater, C.; Lantin, T.; Wellman, S. M.; Jia, L.; Gonzalez, G.; McFaline-Figueroa, J. L.; Wang, Q. bioRxiv 2025.
Dysregulated Mitochondrial Energy Metabolism Drives the Progression of Mucosal Field Effects to Invasive Bladder Cancer. Lee, S.; Jung, S. Y.; Kuś, P.; Bondaruk, J.; Lee, J. G.; Jaksik, R.; Putluri, N.; Dinh, K. N.; Cogdell, D.; Chen, H.; Wang, Y.; Chen, J.; Navai, N.; Dinney, C.; Mendelsohn, C.; McConkey, D.; Behringer, R. R.; Guo, C. C.; Wei, P.; Kimmel, M.; Czerniak, B. The Journal of Pathology 2025, in press.
EmbedOR: Provable Cluster-Preserving Visualizations with Curvature-Based Stochastic Neighbor Embeddings. Saidi, T. L.; Hickok, A.; Rieck, B.; Blumberg, A. J. arXiv 2025.
Multiplexed Single-Cell Transcriptomics Reveals Diverse Phenotypic Outcomes for Pathogenic SHP2 Variants. van Vlimmeren, A. E.; Giglio, R. M.; Jiang, Z.; Lee, M.; McFaline-Figueroa, J. L.; Shah, N. H. bioRxiv 2025.
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Catch up on the latest from our IICD community! Here are some highlights you might have missed on our social channels.
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